We are in tireless pursuit of breakthroughs that improve patients' lives. We create innovations every day to make the world a better place. It was Charles Pfizer's initial vision, and it holds true today. Evidence confirms what intuition tells us: that purpose-driven companies achieve more, are more inventive, recruit and maintain the best talent, and know how to harness the power of those team members. Pfizer's purpose—Breakthroughs that improve patients' lives—powers everything we do and reflects our passion for building on our legacy as one of the most meaningful contributors of good to the world. Each word in our purpose has significance and embodies the value we aim to bring to patients and society. Our purpose guarantees that patients continue to be at the centre of all we do. We embody our purpose by finding the best science in the world, working with others in the healthcare system to enhance access to our medicines, utilizing digital technologies to enhance our drug discovery and development, as well as patient outcomes, and leading the conversation to advocate for pro-innovation/pro-patient policies. Every determination we make, and every action we take is done with the patient in mind—and to foster an environment where breakthroughs can flourish.