We are in constant pursuit of breakthroughs that improve patients' lives. We innovate each day to make the world a healthier place. It was Charles Pfizer's founding vision, and it remains true today. Research confirms what intuition tells us: that purpose-driven companies deliver better results, are more inventive, draw and keep the best people, and know how to unleash the power of those individuals. Pfizer's purpose—Breakthroughs that change patients' lives—powers everything we do and demonstrates our passion for building on our legacy as one of the most important contributors of good to the world. Each word in our purpose has importance and embodies the value we aim to bring to patients and society. Our purpose ensures that patients remain at the centre of all we do. We fulfill our purpose by finding the best science in the world, collaborating with others in the healthcare system to increase access to our medicines, employing digital technologies to enhance our drug discovery and development, as well as patient outcomes, and spearheading the conversation to advocate for pro-innovation/pro-patient policies. Every determination we make, and every action we take is done with the patient in mind—and to nurture an environment where breakthroughs can thrive.