We're in constant pursuit of breakthroughs that improve patients' lives. We innovate every day to make the world a better place. It was Charles Pfizer's initial vision, and it holds true today. Studies show what intuition tells us: that purpose-driven companies perform better, are more innovative, attract and retain the best professionals, and know how to unleash the power of those people. Pfizer's purpose—Breakthroughs that change patients' lives—drives everything we do and shows our passion for building on our legacy as one of the most significant contributors of good to the world. Each word in our purpose has importance and represents the value we aim to bring to patients and society. Our purpose guarantees that patients continue to be at the centre of all we do. We live our purpose by finding the best science in the world, working with others in the healthcare system to increase access to our medicines, utilizing digital technologies to improve our drug discovery and development, as well as patient outcomes, and leading the conversation to advocate for pro-innovation/pro-patient policies. Every determination we make, and every action we take is done with the patient in mind—and to nurture an environment where breakthroughs can thrive.