We are in relentless pursuit of breakthroughs that transform patients' lives. We drive innovation each day to make the world a better place. It was Charles Pfizer's initial vision, and it still holds true today. Research confirms what intuition tells us: that purpose-driven companies achieve more, are more innovative, attract and retain the best professionals, and know how to harness the power of those team members. Pfizer's purpose—Breakthroughs that improve patients' lives—powers everything we do and reflects our passion for growing our legacy as one of the most important contributors of good to the world. Each word in our purpose has significance and reflects the value we strive to bring to patients and society. Our purpose guarantees that patients continue to be at the centre of all we do. We fulfill our purpose by seeking the best science in the world, working with others in the healthcare system to increase access to our medicines, using digital technologies to improve our drug discovery and development, as well as patient outcomes, and leading the conversation to advocate for pro-innovation/pro-patient policies. Every determination we make, and every action we take is done with the patient in mind—and to create an environment where breakthroughs can thrive.