We are in tireless pursuit of breakthroughs that change patients' lives. We create innovations each day to make the world a better place. This was Charles Pfizer's original vision, and it holds true today. Studies show what we instinctively know: that purpose-driven companies perform better, are more innovative, recruit and maintain the best people, and know how to maximize the power of those individuals. Pfizer's purpose—Breakthroughs that change patients' lives—powers everything we do and reflects our passion for growing our legacy as one of the most meaningful contributors of good to the world. Each word in our purpose has importance and embodies the value we strive to bring to patients and society. Our purpose guarantees that patients stay at the centre of all we do. We embody our purpose by seeking the best science in the world, working with others in the healthcare system to enhance access to our medicines, employing digital technologies to improve our drug discovery and development, as well as patient outcomes, and spearheading the conversation to advocate for pro-innovation/pro-patient policies. Every determination we make, and every move we take is done with the patient in mind—and to create an environment where breakthroughs can flourish.