We are in constant pursuit of breakthroughs that change patients' lives. We create innovations daily to make the world a healthier place. This was Charles Pfizer's initial vision, and it holds true today. Studies show what intuition tells us: that purpose-driven companies deliver better results, are more inventive, attract and retain the best people, and know how to maximize the power of those people. Pfizer's purpose—Breakthroughs that improve patients' lives—powers everything we do and reflects our passion for expanding our legacy as one of the most meaningful contributors of good to the world. Each word in our purpose has importance and reflects the value we strive to bring to patients and society. Our purpose guarantees that patients remain at the centre of all we do. We fulfill our purpose by seeking the best science in the world, collaborating with others in the healthcare system to improve access to our medicines, utilizing digital technologies to improve our drug discovery and development, as well as patient outcomes, and spearheading the conversation to push for pro-innovation/pro-patient policies. Every determination we make, and every move we take is done with the patient in mind—and to foster an environment where breakthroughs can thrive.