We are in relentless pursuit of breakthroughs that improve patients' lives. We innovate daily to make the world a better place. This was Charles Pfizer's initial vision, and it remains true today. Evidence confirms what intuition tells us: that purpose-driven companies achieve more, are more inventive, recruit and maintain the best professionals, and know how to maximize the power of those team members. Pfizer's purpose—Breakthroughs that improve patients' lives—powers everything we do and demonstrates our passion for expanding our legacy as one of the most significant contributors of good to the world. Each word in our purpose has meaning and reflects the value we strive to bring to patients and society. Our purpose ensures that patients stay at the centre of all we do. We live our purpose by seeking the best science in the world, working with others in the healthcare system to improve access to our medicines, utilizing digital technologies to enhance our drug discovery and development, as well as patient outcomes, and spearheading the conversation to push for pro-innovation/pro-patient policies. Every determination we make, and every step we take is done with the patient in mind—and to nurture an environment where breakthroughs can thrive.