We are in relentless pursuit of breakthroughs that improve patients' lives. We drive innovation daily to make the world a healthier place. It was Charles Pfizer's original vision, and it remains true today. Research confirms what intuition tells us: that purpose-driven companies perform better, are more inventive, attract and retain the best talent, and know how to unleash the power of those team members. Pfizer's purpose—Breakthroughs that change patients' lives—powers everything we do and demonstrates our passion for expanding our legacy as one of the most important contributors of good to the world. Each word in our purpose has meaning and reflects the value we aim to bring to patients and society. Our purpose makes certain that patients stay at the centre of all we do. We live our purpose by seeking the best science in the world, working with others in the healthcare system to improve access to our medicines, employing digital technologies to advance our drug discovery and development, as well as patient outcomes, and leading the conversation to advocate for pro-innovation/pro-patient policies. Every choice we make, and every move we take is done with the patient in mind—and to create an environment where breakthroughs can thrive.