We are in constant pursuit of breakthroughs that change patients' lives. We drive innovation daily to make the world a better place. It was Charles Pfizer's initial vision, and it holds true today. Research confirms what we instinctively know: that purpose-driven companies perform better, are more inventive, draw and keep the best people, and know how to maximize the power of those individuals. Pfizer's purpose—Breakthroughs that improve patients' lives—powers everything we do and demonstrates our passion for expanding our legacy as one of the most meaningful contributors of good to the world. Each word in our purpose has significance and reflects the value we aim to bring to patients and society. Our purpose ensures that patients continue to be at the centre of all we do. We live our purpose by finding the best science in the world, partnering with others in the healthcare system to enhance access to our medicines, utilizing digital technologies to enhance our drug discovery and development, as well as patient outcomes, and driving the conversation to advocate for pro-innovation/pro-patient policies. Every decision we make, and every action we take is done with the patient in mind—and to nurture an environment where breakthroughs can prosper.