We are in relentless pursuit of breakthroughs that transform patients' lives. We drive innovation daily to make the world a healthier place. This was Charles Pfizer's original vision, and it still holds true today. Evidence confirms what intuition tells us: that purpose-driven companies deliver better results, are more innovative, recruit and maintain the best professionals, and know how to maximize the power of those individuals. Pfizer's purpose—Breakthroughs that improve patients' lives—powers everything we do and shows our passion for growing our legacy as one of the most meaningful contributors of good to the world. Each word in our purpose has importance and represents the value we work to bring to patients and society. Our purpose makes certain that patients continue to be at the centre of all we do. We live our purpose by seeking the best science in the world, collaborating with others in the healthcare system to enhance access to our medicines, utilizing digital technologies to improve our drug discovery and development, as well as patient outcomes, and spearheading the conversation to advocate for pro-innovation/pro-patient policies. Every choice we make, and every step we take is done with the patient in mind—and to foster an environment where breakthroughs can thrive.