We are in relentless pursuit of breakthroughs that change patients' lives. We innovate daily to make the world a healthier place. This was Charles Pfizer's original vision, and it remains true today. Research confirms what intuition tells us: that purpose-driven companies perform better, are more inventive, attract and retain the best professionals, and know how to unleash the power of those individuals. Pfizer's purpose—Breakthroughs that change patients' lives—powers everything we do and demonstrates our passion for expanding our legacy as one of the most important contributors of good to the world. Each word in our purpose has importance and embodies the value we aim to bring to patients and society. Our purpose guarantees that patients continue to be at the centre of all we do. We live our purpose by sourcing the best science in the world, partnering with others in the healthcare system to improve access to our medicines, using digital technologies to advance our drug discovery and development, as well as patient outcomes, and leading the conversation to push for pro-innovation/pro-patient policies. Every determination we make, and every move we take is done with the patient in mind—and to create an environment where breakthroughs can thrive.