We're in relentless pursuit of breakthroughs that improve patients' lives. We create innovations each day to make the world a healthier place. This was Charles Pfizer's initial vision, and it holds true today. Evidence confirms what we instinctively know: that purpose-driven companies perform better, are more creative, draw and keep the best talent, and know how to harness the power of those team members. Pfizer's purpose—Breakthroughs that improve patients' lives—powers everything we do and reflects our passion for expanding our legacy as one of the most important contributors of good to the world. Each word in our purpose has importance and represents the value we aim to bring to patients and society. Our purpose makes certain that patients stay at the centre of all we do. We fulfill our purpose by sourcing the best science in the world, partnering with others in the healthcare system to enhance access to our medicines, utilizing digital technologies to enhance our drug discovery and development, as well as patient outcomes, and driving the conversation to advocate for pro-innovation/pro-patient policies. Every determination we make, and every action we take is done with the patient in mind—and to foster an environment where breakthroughs can thrive.