We are in constant pursuit of breakthroughs that transform patients' lives. We create innovations every day to make the world a healthier place. This was Charles Pfizer's founding vision, and it still holds true today. Evidence confirms what intuition tells us: that purpose-driven companies perform better, are more creative, draw and keep the best people, and know how to maximize the power of those team members. Pfizer's purpose—Breakthroughs that change patients' lives—fuels everything we do and demonstrates our passion for growing our legacy as one of the most important contributors of good to the world. Each word in our purpose has meaning and represents the value we aim to bring to patients and society. Our purpose ensures that patients continue to be at the centre of all we do. We live our purpose by finding the best science in the world, collaborating with others in the healthcare system to enhance access to our medicines, employing digital technologies to advance our drug discovery and development, as well as patient outcomes, and driving the conversation to advocate for pro-innovation/pro-patient policies. Every determination we make, and every action we take is done with the patient in mind—and to foster an environment where breakthroughs can thrive.