We are in constant pursuit of breakthroughs that change patients' lives. We drive innovation daily to make the world a more healthy place. This was Charles Pfizer's original vision, and it remains true today. Evidence confirms what we instinctively know: that purpose-driven companies deliver better results, are more inventive, recruit and maintain the best talent, and know how to harness the power of those team members. Pfizer's purpose—Breakthroughs that improve patients' lives—powers everything we do and shows our passion for expanding our legacy as one of the most meaningful contributors of good to the world. Each word in our purpose has importance and reflects the value we work to bring to patients and society. Our purpose makes certain that patients remain at the centre of all we do. We fulfill our purpose by seeking the best science in the world, collaborating with others in the healthcare system to increase access to our medicines, using digital technologies to advance our drug discovery and development, as well as patient outcomes, and driving the conversation to advocate for pro-innovation/pro-patient policies. Every decision we make, and every step we take is done with the patient in mind—and to foster an environment where breakthroughs can flourish.