We are in relentless pursuit of breakthroughs that transform patients' lives. We drive innovation every day to make the world a better place. It was Charles Pfizer's initial vision, and it holds true today. Evidence confirms what intuition tells us: that purpose-driven companies achieve more, are more innovative, attract and retain the best talent, and know how to unleash the power of those individuals. Pfizer's purpose—Breakthroughs that improve patients' lives—fuels everything we do and shows our passion for expanding our legacy as one of the most important contributors of good to the world. Each word in our purpose has importance and reflects the value we strive to bring to patients and society. Our purpose guarantees that patients continue to be at the centre of all we do. We embody our purpose by seeking the best science in the world, collaborating with others in the healthcare system to increase access to our medicines, utilizing digital technologies to enhance our drug discovery and development, as well as patient outcomes, and spearheading the conversation to push for pro-innovation/pro-patient policies. Every determination we make, and every step we take is done with the patient in mind—and to foster an environment where breakthroughs can flourish.