We are in relentless pursuit of breakthroughs that improve patients' lives. We create innovations every day to make the world a more healthy place. This was Charles Pfizer's initial vision, and it holds true today. Evidence confirms what intuition tells us: that purpose-driven companies perform better, are more inventive, attract and retain the best talent, and know how to maximize the power of those team members. Pfizer's purpose—Breakthroughs that transform patients' lives—powers everything we do and reflects our passion for building on our legacy as one of the most meaningful contributors of good to the world. Each word in our purpose has importance and reflects the value we aim to bring to patients and society. Our purpose ensures that patients stay at the centre of all we do. We embody our purpose by seeking the best science in the world, working with others in the healthcare system to enhance access to our medicines, utilizing digital technologies to enhance our drug discovery and development, as well as patient outcomes, and spearheading the conversation to push for pro-innovation/pro-patient policies. Every determination we make, and every step we take is done with the patient in mind—and to nurture an environment where breakthroughs can thrive.