We're in constant pursuit of breakthroughs that transform patients' lives. We innovate each day to make the world a healthier place. It was Charles Pfizer's initial vision, and it remains true today. Studies show what intuition tells us: that purpose-driven companies perform better, are more creative, draw and keep the best talent, and know how to unleash the power of those individuals. Pfizer's purpose—Breakthroughs that improve patients' lives—drives everything we do and shows our passion for building on our legacy as one of the most significant contributors of good to the world. Each word in our purpose has significance and represents the value we work to bring to patients and society. Our purpose ensures that patients continue to be at the centre of all we do. We fulfill our purpose by sourcing the best science in the world, collaborating with others in the healthcare system to enhance access to our medicines, employing digital technologies to improve our drug discovery and development, as well as patient outcomes, and spearheading the conversation to advocate for pro-innovation/pro-patient policies. Every determination we make, and every step we take is done with the patient in mind—and to nurture an environment where breakthroughs can thrive.