We are in tireless pursuit of breakthroughs that transform patients' lives. We create innovations daily to make the world a healthier place. It was Charles Pfizer's original vision, and it still holds true today. Research confirms what intuition tells us: that purpose-driven companies achieve more, are more innovative, recruit and maintain the best people, and know how to unleash the power of those individuals. Pfizer's purpose—Breakthroughs that transform patients' lives—fuels everything we do and shows our passion for building on our legacy as one of the most significant contributors of good to the world. Each word in our purpose has importance and embodies the value we aim to bring to patients and society. Our purpose ensures that patients continue to be at the centre of all we do. We live our purpose by finding the best science in the world, partnering with others in the healthcare system to improve access to our medicines, employing digital technologies to advance our drug discovery and development, as well as patient outcomes, and leading the conversation to advocate for pro-innovation/pro-patient policies. Every determination we make, and every move we take is done with the patient in mind—and to create an environment where breakthroughs can flourish.