We are in constant pursuit of breakthroughs that improve patients' lives. We create innovations daily to make the world a better place. This was Charles Pfizer's initial vision, and it still holds true today. Research confirms what intuition tells us: that purpose-driven companies achieve more, are more innovative, draw and keep the best talent, and know how to maximize the power of those people. Pfizer's purpose—Breakthroughs that improve patients' lives—powers everything we do and shows our passion for building on our legacy as one of the most important contributors of good to the world. Each word in our purpose has significance and embodies the value we aim to bring to patients and society. Our purpose ensures that patients stay at the centre of all we do. We fulfill our purpose by seeking the best science in the world, working with others in the healthcare system to improve access to our medicines, using digital technologies to enhance our drug discovery and development, as well as patient outcomes, and driving the conversation to campaign for pro-innovation/pro-patient policies. Every determination we make, and every action we take is done with the patient in mind—and to create an environment where breakthroughs can flourish.